Shop a large selection of Proteins A-Z products and learn more about enQuireBio™ Recombinant Human TOMM40, homolog Protein 50μg enQuireBio™ Recombinant Other articles where TOMM40 is discussed: Alzheimer disease: Genetic variants: …of a gene known as TOMM40 (translocase of outer mitochondrial membrane 40 homolog [yeast]) can be used to provide additional information about the risk of Alzheimer disease and to predict the age of onset. There are several forms of this gene, which differ in their length due to variations that… 16/06/2019 TOMM40 variants in Alzheimer's disease was suggested, comparative contribution of the TOMM40‐APOE variants in the regulation of body weight remains elusive. We examined additive effects of rs2075650 and rs157580 TOMM40 variants and rs429358 and rs7412 APOE variants coding the ε2/ε3/ε4 polymorphism on body mass index (BMI) in age‐aggregated and age‐stratified cohort‐specific …

Genome‐wide association studies (GWAS) also report an AD‐increasing effect of the rs2075650 (TOMM40) minor allele and AD‐decreasing effect of the rs157580  

An intronic poly-T in TOMM40, rs10524523, is linked to age-of-onset of sporadic Alzheimer's disease. •. The allele lengths are Short (S), Long (L) or Very long  2) and in linkage disequilibrium with APOE is the TOMM40 gene. A poly T repeat in an intronic polymorphism (rs10524523) (intron 6) in the TOMM40 gene, which   TOMM40 is the channel-forming subunit of the translocase of the mitochondrial outer membrane (TOM) complex that is essential for protein import into  TOMM40 also impacts brain areas vulnerable in AD, by downstream apoptotic processes that forego extracellular amyloid beta aggregation. The present paper  

Function. TOMM40 codes for a protein that is embedded into outer membranes of mitochondria and is required for the movement of proteins into mitochondria.More precisely, TOMM40 is the channel-forming subunit of a translocase of the mitochondrial outer membrane that is essential for protein transport into mitochondria. [3]Clinical significance. In humans, certain alleles of this gene have been

Anti-TOMM40 antibody produced in rabbit is polyclonal, unconjugated and is suitable for immunofluorescence, immunohistochemistry.

Translocase of outer mitochondrial membrane 40 homolog (yeast), also known as TOMM40, is a protein which in humans is encoded by the TOMM40 gene.

Expression of TOMM40 (C19orf1, D19S1177E, PER-EC1, PEREC1, TOM40) in cancer tissue. The cancer tissue page shows antibody staining of the protein in 20 different cancers. Confocal micrograph of HeLa cells visulazed by indirect immunocytochemistry for mitochondria in green with an Anti-TOMM40 antibody and nuclei in blue with Dapi. Laboratory Junior Group (G5) / CNRS. UMR3691; Paris 5; Biologie mitochondriale Département de Biologie cellulaire et infection UMR: Dynamique cellulaire physiologique et pathologique . Timothy Wai. Head. UMR: Dynamique cellulaire Lapin TOMM40 Polyclonal anticorps pour IHC, ELISA, WB. Order anti-TOMM40 anticorps ABIN1093786. The TOMM40 and APOE genes are in high LD, 17, 18 which may obscure disease risk associated with other APOE ɛ4-independent variants in the region. Phylogenetic analysis has been used previously to

Invitrogen Anti-TOMM40 Polyclonal, Catalog # PA5-57575. Tested in Western Blot (WB), Immunofluorescence (IF), Immunocytochemistry (ICC) and 

GeneCards Summary for TOMM40 Gene. TOMM40 (Translocase Of Outer Mitochondrial Membrane 40) is a Protein Coding gene. Diseases associated with   TOMM40 translocase of outer mitochondrial membrane 40 [ (human)]. Gene ID: 10452, updated on 19-Jul-2020 

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